Sildenafil: myths, facts, and what to do

Blister pack of sildenafil tablets next to a glass of water and a medical information leaflet

“Sildenafil”: myths, facts, and what to do

Disclaimer: This article is for educational purposes only and does not replace medical advice. Sildenafil is a prescription medicine in many countries. Decisions about diagnosis and treatment of erectile dysfunction (ED) or other conditions should be made with a qualified healthcare professional.

Key takeaways (TL;DR)

  • Sildenafil (brand name Viagra® and generics) is a PDE5 inhibitor used mainly for erectile dysfunction and, at different dosing, for pulmonary arterial hypertension.
  • It works by enhancing the natural erectile response to sexual stimulation; it does not cause automatic erections.
  • It is generally effective for many men with ED, but not for everyone—underlying health issues matter.
  • Serious interactions exist, especially with nitrates and certain heart medications.
  • Side effects are usually mild and temporary, but some red flags require urgent care.

Myths and facts

Myth: Sildenafil increases sexual desire (libido)

Fact: Sildenafil improves blood flow to the penis by inhibiting phosphodiesterase type 5 (PDE5). It does not directly increase sexual desire or arousal.

Why people think so: The drug is often portrayed as a “sex booster,” and successful erections may be confused with higher libido.

Practical action: If low desire is the main issue, discuss hormonal, psychological, or relationship factors with a clinician. You can also read more on men’s sexual health basics for context.

Myth: It works instantly

Fact: Sildenafil typically takes some time to start working and requires sexual stimulation. Onset and duration vary among individuals.

Why people think so: Marketing and anecdotes often oversimplify timing.

Practical action: Plan ahead and follow your clinician’s instructions. Avoid heavy meals before use, as they may delay effect.

Myth: The higher the dose, the better the result

Fact: Higher doses may increase side effects without proportionally improving efficacy. Optimal dosing depends on individual response and tolerability.

Why people think so: There is a common belief that “more equals stronger.”

Practical action: Never adjust the dose on your own. If results are unsatisfactory, consult your prescriber to review technique, timing, and possible underlying conditions.

Myth: Sildenafil is safe for everyone

Fact: It is contraindicated with nitrates (e.g., nitroglycerin) and should be used cautiously in certain cardiovascular conditions.

Why people think so: Wide availability of generics may create a perception of universal safety.

Practical action: Inform your doctor about all medications and heart history. See our overview on cardiovascular risk and sexual activity before starting treatment.

Myth: If it doesn’t work once, it never will

Fact: Response may improve with correct use, repeated attempts, or management of contributing factors (e.g., diabetes, anxiety).

Why people think so: Initial anxiety or incorrect timing can lead to a disappointing first experience.

Practical action: Review instructions carefully. Address lifestyle factors such as smoking, alcohol use, and physical inactivity.

Myth: Sildenafil causes permanent erections

Fact: Prolonged erection (priapism) is rare but possible. Most erections subside after sexual activity.

Why people think so: Media stories often focus on rare adverse events.

Practical action: Seek urgent medical care if an erection lasts more than 4 hours.

Myth: It’s only for older men

Fact: ED can affect men of various ages. Causes include psychological stress, metabolic disease, medication effects, and more.

Why people think so: ED prevalence increases with age, reinforcing stereotypes.

Practical action: Younger men with ED should consider screening for cardiometabolic risks. Learn more in our guide on early signs of vascular disease.

Myth: Generic sildenafil is inferior to brand-name Viagra

Fact: Approved generics contain the same active ingredient and must meet regulatory standards for bioequivalence.

Why people think so: Branding and price differences may influence perception.

Practical action: Purchase from licensed pharmacies. Avoid unverified online sellers due to counterfeit risk.

Myth: It protects against sexually transmitted infections (STIs)

Fact: Sildenafil has no protective effect against STIs.

Why people think so: Improved sexual performance may be mistakenly associated with overall “sexual protection.”

Practical action: Use barrier protection and consider regular screening. See our resource on STI prevention and testing.

Evidence snapshot

Statement Evidence level Comment
Sildenafil improves erectile function in many men with ED High (randomized controlled trials) Supported by multiple clinical trials and guideline recommendations
Requires sexual stimulation to work High Mechanism depends on nitric oxide release during arousal
Unsafe with nitrates High Risk of severe hypotension; contraindicated
May help in pulmonary arterial hypertension (different regimen) High Approved indication under medical supervision
Improves libido directly Low/Not supported No direct effect on sexual desire established

Safety: when you cannot wait

Seek urgent medical care if you experience:

  • Chest pain or severe shortness of breath after taking sildenafil
  • An erection lasting more than 4 hours (possible priapism)
  • Sudden vision loss in one or both eyes
  • Sudden hearing decrease or loss
  • Fainting or severe dizziness

FAQ

How long does sildenafil last?

Its effects may last several hours, but duration varies. It does not mean a continuous erection; sexual stimulation is still required.

Can women take sildenafil?

Sildenafil is not routinely approved for female sexual dysfunction. Research is ongoing, but evidence remains limited and indications differ.

Is it safe with alcohol?

Small amounts of alcohol may not cause major issues for some people, but alcohol can worsen ED and increase side effects like dizziness.

Can I take it daily?

Some PDE5 inhibitors are designed for daily use, but sildenafil regimens vary. Follow your prescriber’s guidance.

Does it cure erectile dysfunction?

No. It treats symptoms temporarily. Addressing underlying causes—such as diabetes, hypertension, obesity, or psychological stress—is essential.

What if it stops working?

Consult your clinician. Dose adjustment, switching medications, or evaluating new health conditions may be necessary.

Sources

  • U.S. Food and Drug Administration (FDA). Viagra (sildenafil) prescribing information: https://www.accessdata.fda.gov
  • European Medicines Agency (EMA). Sildenafil-containing medicines: https://www.ema.europa.eu
  • American Urological Association (AUA). Erectile Dysfunction Guideline: https://www.auanet.org/guidelines
  • National Health Service (NHS). Sildenafil overview: https://www.nhs.uk/medicines/sildenafil-viagra/
  • Mayo Clinic. Sildenafil (oral route): https://www.mayoclinic.org/drugs-supplements/sildenafil-oral-route/